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Centre for Misfolding Diseases

Publications

Aggregation of α-synuclein splice isoforms through a phase separation pathway
A Röntgen, Z Toprakcioglu, ST Dada, OM Morris, TPJ Knowles, M Vendruscolo
– Science advances
(2025)
11,
eadq5396
A scale-invariant log-normal droplet size distribution below the transition concentration for protein phase separation
T Amico, S Dada, A Lazzari, A Trovato, M Vendruscolo, M Fuxreiter, A Maritan
– eLife
(2024)
13,
A scale-invariant log-normal droplet size distribution below the critical concentration for protein phase separation.
T Amico, ST Dada, A Lazzari, M Brezinova, A Trovato, M Vendruscolo, M Fuxreiter, A Maritan
– eLife
(2024)
13,
RP94214
Pharmacological inhibition of α-synuclein aggregation within liquid condensates
ST Dada, Z Toprakcioglu, MP Cali, A Röntgen, MC Hardenberg, OM Morris, LK Mrugalla, TPJ Knowles, M Vendruscolo
– Nat Commun
(2024)
15,
3835
A deep dive into the liquid droplet state of α-synuclein
ST Dada
(2024)
Pharmacological inhibition of α-synuclein aggregation within liquid condensates
M Vendruscolo, S Dada, Z Toprakcioglu, M Hardenberg, M Cali, L Mrugalla, O Morris, A Roentgen, T Knowles
(2023)
A scale-invariant log-normal droplet size distribution below the critical concentration for protein phase separation
T Amico, S Dada, A Lazzari, M Brezinova, A Trovato, M Vendruscolo, M Fuxreiter, A Maritan
(2023)
Spontaneous nucleation and fast aggregate-dependent proliferation of α-synuclein aggregates within liquid condensates at neutral pH
ST Dada, MC Hardenberg, Z Toprakcioglu, LK Mrugalla, MP Cali, MO McKeon, E Klimont, TCT Michaels, TPJ Knowles, M Vendruscolo
– Proceedings of the National Academy of Sciences
(2023)
120,
e2208792120
Unravelling the kinetics of α-synuclein aggregation via the condensation pathway
ST Dada
– Biophysical Journal
(2022)
121,
353a
Spontaneous nucleation and fast aggregate-dependent proliferation of α-synuclein aggregates within liquid condensates at physiological pH
ST Dada, MC Hardenberg, LK Mrugalla, MO McKeon, E Klimont, TCT Michaels, M Vendruscolo
(2021)
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