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Centre for Misfolding Diseases

Dr Srinivasa Rao Adusumalli

Marie Curie Research Fellow

Publications

Linchpins empower promiscuous electrophiles to enable site-selective modification of histidine and aspartic acid in proteins
DG Rawale, K Thakur, P Sreekumar, S T K, R A, SR Adusumalli, RK Mishra, V Rai
– Chemical Science
(2021)
12,
6732
(doi: 10.1039/d1sc00335f)
A single amino acid Gly-tag enables metal-free protein purification.
L Purushottam, U V B, DG Rawale, M Gujrati, SD Mishra, S T K, NC Reddy, SR Adusumalli, RK Mishra, V Rai
– Chem Sci
(2020)
11,
13137
(doi: 10.1039/d0sc01153c)
Serine-Selective Bioconjugation.
JC Vantourout, SR Adusumalli, KW Knouse, DT Flood, A Ramirez, NM Padial, A Istrate, K Maziarz, JN deGruyter, RR Merchant, JX Qiao, MA Schmidt, MJ Deery, MD Eastgate, PE Dawson, GJL Bernardes, PS Baran
– J Am Chem Soc
(2020)
142,
17236
(doi: 10.1021/jacs.0c05595)
Chemoselective and Site‐Selective Lysine‐Directed Lysine Modification Enables Single‐Site Labeling of Native Proteins
SR Adusumalli, DG Rawale, K Thakur, L Purushottam, NC Reddy, N Kalra, S Shukla, V Rai
– Angewandte Chemie - International Edition
(2020)
59,
10332
(doi: 10.1002/anie.202000062)
Chemical Methods for Selective Labeling of Proteins
DG Rawale, K Thakur, SR Adusumalli, V Rai
– European Journal of Organic Chemistry
(2019)
2019,
6749
(doi: 10.1002/ejoc.201900801)
Ethynylbenziodoxolone Reactivity in Cysteine Bioconjugation
SR Adusumalli, GJL Bernardes
– Chem
(2019)
5,
1932
(doi: 10.1016/j.chempr.2019.07.014)
Single-site glycine-specific labeling of proteins
L Purushottam, SR Adusumalli, U Singh, VB Unnikrishnan, DG Rawale, M Gujrati, RK Mishra, V Rai
– Nature Communications
(2019)
10,
2539
(doi: 10.1038/s41467-019-10503-7)
Single-Site Labeling of Native Proteins Enabled by a Chemoselective and Site-Selective Chemical Technology.
SR Adusumalli, DG Rawale, U Singh, P Tripathi, R Paul, N Kalra, RK Mishra, S Shukla, V Rai
– Journal of the American Chemical Society
(2018)
140,
15114
(doi: 10.1021/jacs.8b10490)
Aldehydes can switch the chemoselectivity of electrophiles in protein labeling.
SR Adusumalli, DG Rawale, V Rai
– Organic & Biomolecular Chemistry
(2018)
16,
9377
(doi: 10.1039/c8ob02897d)
Chemoselective and site-selective peptide and native protein modification enabled by aldehyde auto-oxidation
L Purushottam, SR Adusumalli, M Chilamari, V Rai
– Chem Commun (Camb)
(2017)
53,
959
(doi: 10.1039/c6cc09555k)
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