Rob Scrutton

Publications

Biomolecular condensates sustain pH gradients at equilibrium through charge neutralization.

H Ausserwöger, R Scrutton, CM Fischer, T Sneideris, D Qian, E de Csilléry, I Baronaite, KL Saar, AZ Białek, M Oeller, G Krainer, TM Franzmann, S Wittmann, JM Iglesias-Artola, G Invernizzi, AA Hyman, S Alberti, N Lorenzen, TPJ Knowles

Nat Chem

(2026)

246

(doi: 10.1038/s41557-025-02039-9)

Mapping high resolution, multidimensional phase diagrams of physiological protein condensates

T Agarwal, T Sneideris, F Svara, K Jermakovs, H Coyle, S Qamar, E Kava, R Scrutton, N Pleschka, P Peres, G Cereghetti, E Andrzejewska, A Diaz-Barreiro, G Palmer, AJ Costa-Filho, G Krainer, TP Knowles, J Nixon-Abell

(2025)

(doi: 10.1101/2025.11.24.690258)

Model Agnostic Conditioning of Boltzmann Generators for Peptide Cyclization

B du Pont, A Abrudan, R Scrutton, V Radenkovic, H Zhao, T Knowles

(2025)

(doi: 10.1101/2025.08.15.670426)

Extracellular phase separation mediates storage and release of thyroglobulin in the thyroid follicular lumen

Y Yao, N Erkamp, T Sneideris, X Yang, R Scrutton, MM Schneider, CM Fischer, E Schoenmakers, N Schoenmakers, TPJ Knowles

Communications Biology

(2025)

466

(doi: 10.1038/s42003-025-07909-z)

Protein Condensate Atlas from predictive models of heteromolecular condensate composition

KL Saar, RM Scrutton, K Bloznelyte, AS Morgunov, LL Good, AA Lee, SA Teichmann, TPJ Knowles

Nature Communications

(2024)

5418

(doi: 10.1038/s41467-024-48496-7)

Biomolecular condensates sustain pH gradients at equilibrium through charge neutralisation

(2024)

(doi: 10.1101/2024.05.23.595321)

Linking modulation of bio-molecular phase behaviour with collective interactions

D Qian, H Ausserwoger, WE Arter, RM Scrutton, TJ Welsh, T Kartanas, N Ermann, S Qamar, C Fischer, T Sneideris, P St George-Hyslop, RV Pappu, TPJ Knowles

(2023)

(doi: 10.1101/2023.11.02.565376)

Reversibility and β-sheet formation are decoupled in tau condensate ageing

T Knowles, CM Fischer, I-A Edu, T Sneideris, I Baronaite, Z Toprakcioglu, L-T Deck, D Qian, R Scrutton, J Dreyer, S Wen, D Otzen, S Wu, S Perrett

Proceedings of the National Academy of Sciences of the United States of America

Rob Scrutton

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