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Centre for Misfolding Diseases

Publications

A Fragment-Based Method of Creating Small-Molecule Libraries to Target the Aggregation of Intrinsically Disordered Proteins
P Joshi, S Chia, J Habchi, TPJ Knowles, CM Dobson, M Vendruscolo
– ACS combinatorial science
(2016)
18,
144
Neuroscience: An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic Ab42 aggregates linked with Alzheimer's disease
J Habchi, P Arosio, M Perni, AR Costa, M Yagi-Utsumi, P Joshi, S Chia, SIA Cohen, MBD Müller, S Linse, EAA Nollen, CM Dobson, TPJ Knowles, M Vendruscolo
– Science advances
(2016)
2,
e1501244
Druggability of Intrinsically Disordered Proteins
P Joshi, M Vendruscolo
– Advances in Experimental Medicine and Biology
(2015)
870,
383
Structural and Mechanistic Analyses of the Effects of Small Compounds on Amyloid Beta Self-Assembly
J Habchi, P Joshi, A Spilotros, D Svergun, M Vendruscolo
– BIOPHYSICAL JOURNAL
(2014)
106,
268A
Pathway Analysis of Acinetobacter baylyi: A Combined Bioinformatic and Genomics Approach
S Singh, P Joshi, BA Chopade
– Chemical Biology & Drug Design
(2011)
78,
893

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