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Centre for Misfolding Diseases

Publications

Structural insights into human brachyury DNA recognition and discovery of progressible binders for cancer therapy.
JA Newman, AE Gavard, N Imprachim, H Aitkenhead, HE Sheppard, R Te Poele, PA Clarke, MA Hossain, L Temme, HJ Oh, CI Wells, ZW Davis-Gilbert, P Workman, O Gileadi, DH Drewry
– Nature communications
(2025)
16,
1596
Crystal structures and fragment screening of SARS-CoV-2 NSP14 reveal details of exoribonuclease activation and mRNA capping and provide starting points for antiviral drug development.
N Imprachim, Y Yosaatmadja, JA Newman
– Nucleic acids research
(2022)
51,
475

Postgraduate student

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