Dr Hannes Ausserwöger

Research Assisstant

Publications

Biomolecular function and failure across length scales

H Ausserwoeger

(2024)

Single-molecule digital sizing of proteins in solution.

G Krainer, RPB Jacquat, MM Schneider, TJ Welsh, J Fan, QAE Peter, EA Andrzejewska, G Šneiderienė, MA Czekalska, H Ausserwoeger, L Chai, WE Arter, KL Saar, TW Herling, TM Franzmann, V Kosmoliaptsis, S Alberti, FU Hartl, SF Lee, TPJ Knowles

Nature communications

(2024)

7740

(doi: 10.1038/s41467-024-50825-9)

Solutes unmask differences in clustering versus phase separation of FET proteins.

M Kar, LT Vogel, G Chauhan, S Felekyan, H Ausserwöger, TJ Welsh, F Dar, AR Kamath, TPJ Knowles, AA Hyman, CAM Seidel, RV Pappu

Nat Commun

(2024)

4408

(doi: 10.1038/s41467-024-48775-3)

Biomolecular condensates sustain pH gradients at equilibrium through charge neutralisation

H Ausserwöger, R Scrutton, CM Fischer, T Sneideris, D Qian, E de Csilléry, I Baronaite, KL Saar, AZ Białek, M Oeller, G Krainer, TM Franzmann, S Wittmann, JM Iglesias-Artola, G Invernizzi, AA Hyman, S Alberti, N Lorenzen, TPJ Knowles

(2024)

(doi: 10.1101/2024.05.23.595321)

Nonspecificity fingerprints for clinical-stage antibodies in solution

TW Herling, G Invernizzi, H Ausserwöger, JR Bjelke, T Egebjerg, S Lund, N Lorenzen, TPJ Knowles

Proceedings of the National Academy of Sciences

(2023)

120

e2306700120

(doi: 10.1073/pnas.2306700120)

Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions.

M Kar, LT Vogel, G Chauhan, H Ausserwöger, TJ Welsh, AR Kamath, TPJ Knowles, AA Hyman, CAM Seidel, RV Pappu

(2023)

(doi: 10.21203/rs.3.rs-3252197/v1)

Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions

M Kar, LT Vogel, G Chauhan, H Ausserwöger, TJ Welsh, AR Kamath, TPJ Knowles, AA Hyman, CAM Seidel, RV Pappu

(2023)

(doi: 10.1101/2023.08.11.552963)

Single-molecule digital sizing of proteins in solution

(2023)

(doi: 10.1101/2023.07.12.548675)

Quantifying collective interactions in biomolecular phase separation

H Ausserwöger, D Qian, G Krainer, E de Csilléry, TJ Welsh, T Sneideris, TM Franzmann, S Qamar, NA Erkamp, J Nixon-Abell, M Kar, P St George-Hyslop, AA Hyman, S Alberti, RV Pappu, TPJ Knowles

(2023)

(doi: 10.1101/2023.05.31.543137)

Surface patches induce nonspecific binding and phase separation of antibodies.

H Ausserwöger, G Krainer, TJ Welsh, N Thorsteinson, E de Csilléry, T Sneideris, MM Schneider, T Egebjerg, G Invernizzi, TW Herling, N Lorenzen, TPJ Knowles

Proceedings of the National Academy of Sciences of the United States of America

(2023)

120

e2210332120

(doi: 10.1073/pnas.2210332120)

Dr Hannes Ausserwöger

Research Assisstant

Publications

Postdoctoral researcher

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Research at Cambridge