Catherine Kejia Xu

Research Associate

Publications

The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells

R Cascella, SW Chen, A Bigi, JD Camino, CK Xu, CM Dobson, F Chiti, N Cremades, C Cecchi

Nat Commun

(2021)

1814

(doi: 10.1038/s41467-021-21937-3)

A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers

R Cataldi, S Chia, K Pisani, FS Ruggeri, CK Xu, T Šneideris, M Perni, S Sarwat, P Joshi, JR Kumita, S Linse, J Habchi, TPJ Knowles, B Mannini, CM Dobson, M Vendruscolo

Communications Biology

(2021)

(doi: 10.1038/s42003-020-01490-3)

Interactions of α-synuclein oligomers with lipid membranes

G Musteikytė, AK Jayaram, CK Xu, M Vendruscolo, G Krainer, TPJ Knowles

Biochimica et biophysica acta. Biomembranes

(2020)

1863

183536

(doi: 10.1016/j.bbamem.2020.183536)

Rapid Structural, Kinetic, and Immunochemical Analysis of Alpha-Synuclein Oligomers in Solution

WE Arter, CK Xu, M Castellana-Cruz, TW Herling, G Krainer, KL Saar, JR Kumita, CM Dobson, TPJ Knowles

Nano letters

(2020)

8163

(doi: 10.1021/acs.nanolett.0c03260)

Biophysical approaches to characterising protein-protein interactions and intermediate species in protein aggregation

C Xu

(2020)

(doi: 10.17863/CAM.65349)

Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies.

S Linse, T Scheidt, K Bernfur, M Vendruscolo, CM Dobson, SIA Cohen, E Sileikis, M Lundqvist, F Qian, T O'Malley, T Bussiere, PH Weinreb, CK Xu, G Meisl, SRA Devenish, TPJ Knowles, O Hansson

Nature Structural & Molecular Biology

(2020)

1125

(doi: 10.1038/s41594-020-0505-6)

Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism.

R Limbocker, B Mannini, FS Ruggeri, R Cascella, CK Xu, M Perni, S Chia, SW Chen, J Habchi, A Bigi, RP Kreiser, AK Wright, JA Albright, T Kartanas, JR Kumita, N Cremades, M Zasloff, C Cecchi, TPJ Knowles, F Chiti, M Vendruscolo, CM Dobson

Communications Biology

(2020)

435

(doi: 10.1038/s42003-020-01140-8)

Templating S100A9 amyloids on Aβ fibrillar surfaces revealed by charge detection mass spectrometry, microscopy, kinetic and microfluidic analyses.

J Pansieri, IA Iashchishyn, H Fakhouri, L Ostojić, M Malisauskas, G Musteikyte, V Smirnovas, MM Schneider, T Scheidt, CK Xu, G Meisl, TPJ Knowles, E Gazit, R Antoine, LA Morozova-Roche

Chemical Science

(2020)

7031

(doi: 10.1039/c9sc05905a)

ThX – a next-generation probe for the early detection of amyloid aggregates

L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, L Tutton, R Cliffe, B Keenlyside, D Klenerman, CM Dobson, CA Hunter, KH Müller, K O'Holleran, SE Bohndiek, TN Snaddon, SF Lee

Chemical Science

(2020)

4578

(doi: 10.1039/c9sc04730a)

Rapid Fractionation and Characterisation of Alpha-Synuclein Oligomers in Solution

WE Arter, CK Xu, M Castellana-Cruz, TW Herling, G Krainer, KL Saar, JR Kumita, CM Dobson, TPJ Knowles

(2020)

2020.03.10.985804

(doi: 10.1101/2020.03.10.985804)

Catherine Kejia Xu

Research Associate

Publications

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Study at Cambridge

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Research at Cambridge