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Centre for Misfolding Diseases

Royal Society Newton Fellow

Publications

Sequential dual site-selective protein labelling enabled by lysine modification.
MJ Matos, L Brown, B Bernardim, A Guerreiro, G Jiménez-Osés, GJL Bernardes
– Bioorganic & Medicinal Chemistry
(2020)
28,
115783
Precise Installation of Diazo-Tagged Side-Chains on Proteins to Enable In Vitro and In-Cell Site-Specific Labeling
B Bernardim, L Dunsmore, H Li, B Hocking, R Nuñez-Franco, CD Navo, G Jiménez-Osés, ACB Burtoloso, GJL Bernardes
– Bioconjugate Chemistry
(2020)
31,
1604
A Microfluidic Co-Flow Route for Human Serum Albumin-Drug-Nanoparticle Assembly
TA Hakala, S Davies, Z Toprakcioglu, B Bernardim, GJL Bernardes, TPJ Knowles
– Chemistry - A European Journal
(2020)
26,
5965
Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification.
PR Lindstedt, FA Aprile, MJ Matos, M Perni, JB Bertoldo, B Bernardim, Q Peter, G Jiménez-Osés, TPJ Knowles, CM Dobson, F Corzana, M Vendruscolo, GJL Bernardes
– ACS central science
(2019)
5,
1417
Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine-Selective Protein Modification and Charge Modulation
MJ Matos, CD Navo, T Hakala, X Ferhati, A Guerreiro, D Hartmann, B Bernardim, KL Saar, I Compañón, F Corzana, TPJ Knowles, G Jiménez-Osés, GJL Bernardes
– Angewandte Chemie (International ed. in English)
(2019)
58,
6640
Efficient and irreversible antibody-cysteine bioconjugation using carbonylacrylic reagents
B Bernardim, MJ Matos, X Ferhati, I Compañón, A Guerreiro, P Akkapeddi, ACB Burtoloso, G Jiménez-Osés, F Corzana, GJL Bernardes
– Nature Protocols
(2019)
14,
86
New methodologies in organic synthesis using the Wolff rearrangement from unsaturated diazoketones
B Bernardim de Souza
(2017)
Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents.
B Bernardim, PMSD Cal, MJ Matos, BL Oliveira, N Martínez-Sáez, IS Albuquerque, E Perkins, F Corzana, ACB Burtoloso, G Jiménez-Osés, GJL Bernardes
– Nature Communications
(2016)
7,
13128
Divergent Roles of Urea and Phosphoric Acid Derived Catalysts in Reactions of Diazo Compounds
B Bernardim, ED Couch, AM Hardman-Baldwin, ACB Burtoloso, AE Mattson
– Synthesis (Germany)
(2016)
48,
677
Advances in the Enantioselective Metal-catalyzed N-H and O-H Insertion Reactions with Diazocarbonyl Compounds
ACB Burtoloso, JV Santiago, B Bernardim, AG Talero
– Current Organic Synthesis
(2015)
12,
650
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Postdoctoral researcher

Telephone number

01223 336338