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Centre for Misfolding Diseases

Dr Alexander Buell

Publications

A rationally designed six-residue swap generates comparability in the aggregation behavior of α-synuclein and β-synuclein
C Roodveldt, A Andersson, EJ De Genst, A Labrador-Garrido, AK Buell, CM Dobson, GG Tartaglia, M Vendruscolo
– Biochemistry
(2012)
51,
8771
(doi: 10.1021/bi300558q)
Detailed analysis of the energy barriers for amyloid fibril growth
AK Buell, A Dhulesia, DA White, TPJ Knowles, CM Dobson, ME Welland
– Angew Chem Int Ed Engl
(2012)
51,
5247
(doi: 10.1002/anie.201108040)
Measuring the Kinetics of Amyloid Fibril Elongation Using Quartz Crystal Microbalances
AK Buell, CM Dobson, ME Welland
– Methods Mol Biol
(2012)
849,
101
(doi: 10.1007/978-1-61779-551-0_8)
Probing small molecule binding to amyloid fibrils
AK Buell, EK Esbjörner, PJ Riss, DA White, FI Aigbirhio, G Toth, ME Welland, CM Dobson, TPJ Knowles
– Physical chemistry chemical physics : PCCP
(2011)
13,
20044
(doi: 10.1039/c1cp22283j)
Binding of the Molecular Chaperone alpha B-Crystallin to A beta Amyloid Fibrils Inhibits Fibril Elongation
SL Shammas, CA Waudby, S Wang, AK Buell, TPJ Knowles, H Ecroyd, ME Welland, JA Carver, CM Dobson, S Meehan
– Biophys J
(2011)
101,
1681
(doi: 10.1016/j.bpj.2011.07.056)
Population of Nonnative States of Lysozyme Variants Drives Amyloid Fibril Formation
AK Buell, A Dhulesia, MF Mossuto, N Cremades, JR Kumita, M Dumoulin, ME Welland, TPJ Knowles, X Salvatella, CM Dobson
– Journal of the American Chemical Society
(2011)
133,
7737
(doi: 10.1021/ja109620d)
Relationship between Prion Propensity and the Rates of Individual Molecular Steps of Fibril Assembly*
Y-Q Wang, AK Buell, X-Y Wang, ME Welland, CM Dobson, TPJ Knowles, S Perrett
– Journal of Biological Chemistry
(2011)
286,
12101
(doi: 10.1074/jbc.m110.208934)
Interactions between Amyloidophilic dyes and their relevance to studies of amyloid inhibitors
AK Buell, CM Dobson, TPJ Knowles, ME Welland
– Biophysical Journal
(2010)
99,
3492
(doi: 10.1016/j.bpj.2010.08.074)
Surface attachment of protein fibrils via covalent modification strategies
AK Buell, DA White, C Meier, ME Welland, TPJ Knowles, CM Dobson
– The Journal of Physical Chemistry B
(2010)
114,
10925
(doi: 10.1021/jp101579n)
Frequency factors in a landscape model of filamentous protein aggregation
AK Buell, JR Blundell, CM Dobson, ME Welland, EM Terentjev, TPJ Knowles
– Physical Review Letters
(2010)
104,
228101
(doi: 10.1103/physrevlett.104.228101)
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