Centre for Misfolding Diseases

Dr Alexander Buell

Publications

Probing small molecule binding to amyloid fibrils
AK Buell, EK Esbjörner, PJ Riss, DA White, FI Aigbirhio, G Toth, ME Welland, CM Dobson, TPJ Knowles
Physical Chemistry Chemical Physics
(2011)
13
(doi: 10.1039/c1cp22283j)
Binding of the Molecular Chaperone αB-Crystallin to Aβ Amyloid Fibrils Inhibits Fibril Elongation
SL Shammas, CA Waudby, S Wang, AK Buell, TPJ Knowles, H Ecroyd, ME Welland, JA Carver, CM Dobson, S Meehan
Biophys J
(2011)
101
(doi: 10.1016/j.bpj.2011.07.056)
Population of nonnative states of lysozyme variants drives amyloid fibril formation.
AK Buell, A Dhulesia, MF Mossuto, N Cremades, JR Kumita, M Dumoulin, ME Welland, TPJ Knowles, X Salvatella, CM Dobson
Journal of the American Chemical Society
(2011)
133
(doi: 10.1021/ja109620d)
Relationship between prion propensity and the rates of individual molecular steps of fibril assembly
Y-Q Wang, AK Buell, X-Y Wang, ME Welland, CM Dobson, TPJ Knowles, S Perrett
Journal of Biological Chemistry
(2011)
286
(doi: 10.1074/jbc.m110.208934)
Interactions between amyloidophilic dyes and their relevance to studies of amyloid inhibitors.
AK Buell, CM Dobson, TPJ Knowles, ME Welland
Biophysical Journal
(2010)
99
(doi: 10.1016/j.bpj.2010.08.074)
Surface Attachment of Protein Fibrils via Covalent Modification Strategies
AK Buell, DA White, C Meier, ME Welland, TPJ Knowles, CM Dobson
J Phys Chem B
(2010)
114
(doi: 10.1021/jp101579n)
Frequency Factors in a Landscape Model of Filamentous Protein Aggregation
AK Buell, JR Blundell, CM Dobson, ME Welland, EM Terentjev, TPJ Knowles
Physical Review Letters
(2010)
104
(doi: 10.1103/physrevlett.104.228101)
Protein Aggregation in Crowded Environments
DA White, AK Buell, TPJ Knowles, ME Welland, CM Dobson
Journal of the American Chemical Society
(2010)
132
(doi: 10.1021/ja909997e)
Nanostructured films from hierarchical self-assembly of amyloidogenic proteins.
TPJ Knowles, TW Oppenheim, AK Buell, DY Chirgadze, ME Welland
Nature Nanotechnology
(2010)
5
(doi: 10.1038/nnano.2010.26)
Biosensor-based label-free assays of amyloid growth.
DA White, AK Buell, CM Dobson, ME Welland, TPJ Knowles
FEBS Letters
(2009)
583
(doi: 10.1016/j.febslet.2009.06.008)

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