Publications

Amyloid seeding assays for the selective amplification of tau aggregates from human brain homogenates
M Metrick
(2022)
Computational maturation of a single-domain antibody against Aβ42 aggregation.
J Lin, C Figazzolo, MA Metrick, P Sormanni, M Vendruscolo
Chemical science
(2021)
12
A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases
MA Metrick, NDC Ferreira, E Saijo, A Kraus, K Newell, G Zanusso, M Vendruscolo, B Ghetti, B Caughey
Acta Neuropathologica Communications
(2020)
8
Correction to: 4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration (Acta Neuropathologica, (2020), 139, 1, (63-77), 10.1007/s00401-019-02080-2)
E Saijo, MA Metrick, S Koga, P Parchi, I Litvan, S Spina, A Boxer, JC Rojas, D Galasko, A Kraus, M Rossi, K Newell, G Zanusso, LT Grinberg, WW Seeley, B Ghetti, DW Dickson, B Caughey
Acta Neuropathologica
(2019)
139
Million-fold sensitivity enhancement in proteopathic seed amplification assays for biospecimens by Hofmeister ion comparisons
MA Metrick, N do Carmo Ferreira, E Saijo, AG Hughson, A Kraus, C Orrú, MW Miller, G Zanusso, B Ghetti, M Vendruscolo, B Caughey
Proceedings of the National Academy of Sciences of the United States of America
(2019)
116
4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration.
E Saijo, MA Metrick, S Koga, P Parchi, I Litvan, S Spina, A Boxer, JC Rojas, D Galasko, A Kraus, M Rossi, K Newell, G Zanusso, LT Grinberg, WW Seeley, B Ghetti, DW Dickson, B Caughey
Acta Neuropathologica
(2019)
139
Ultrasensitive RT-QuIC Seed Amplification Assays for Disease-Associated Tau, α-Synuclein, and Prion Aggregates
E Saijo, BR Groveman, A Kraus, M Metrick, CD Orrù, AG Hughson, B Caughey
(2019)
1873
Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease
A Kraus, E Saijo, MA Metrick, K Newell, CJ Sigurdson, G Zanusso, B Ghetti, B Caughey
Acta Neuropathologica
(2018)
137
Hofmeister Ion-Induced Changes in Water Structure Correlate with Changes in Solvation of an Aggregated Protein Complex
TP Light, KM Corbett, MA Metrick, G MacDonald
Langmuir
(2016)
32
Variable-Field Analytical Ultracentrifugation: I. Time-Optimized Sedimentation Equilibrium
J Ma, M Metrick, R Ghirlando, H Zhao, P Schuck
Biophysical journal
(2015)
109

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01223 748845