Publications
Trodusquemine enhances Aβ 42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes
– Nature communications
(2019)
10,
225
(doi: 10.1038/s41467-018-07699-5)
Bacterial production and direct functional screening of expanded molecular libraries for discovering inhibitors of protein aggregation.
– Science Advances
(2019)
5,
eaax5108
(doi: 10.1126/sciadv.aax5108)
Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy.
– J Vis Exp
(2019)
2019,
ARTN e60108
(doi: 10.3791/60108)
Chemical and mechanistic analysis of photodynamic inhibition of Alzheimer's β-amyloid aggregation
– Chemical communications (Cambridge, England)
(2019)
55,
1152
(doi: 10.1039/c8cc09288e)
Endogenous metabolites rescue a C. elegans model of Alzheimer's disease by triggering a heat shock response
– FEBS OPEN BIO
(2019)
9,
225
Stabilization and Characterization of Cytotoxic Aβ40 Oligomers Isolated from an Aggregation Reaction in the Presence of Zinc Ions
– ACS chemical neuroscience
(2018)
9,
2959
(doi: 10.1021/acschemneuro.8b00141)
SAR by kinetics for drug discovery in protein misfolding diseases
– Proceedings of the National Academy of Sciences of the United States of America
(2018)
115,
10245
(doi: 10.1073/pnas.1807884115)
Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity.
– Nature communications
(2018)
9,
3890
(doi: 10.1038/s41467-018-06345-4)
Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes.
– Nature chemistry
(2018)
10,
673
(doi: 10.1038/s41557-018-0031-x)
Chemical Kinetics for Bridging Molecular Mechanisms and Macroscopic Measurements of Amyloid Fibril Formation.
– Annual Review of Physical Chemistry
(2018)
69,
273
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