Research Associate
Education
10/2013 - present University of Cambridge, UK
Doctor of Philosophy (PhD)
10/2011 - 09/2013 Ludwigs-Maximilians-University Munich, Germany
Master of Science Biochemistry
10/2008 - 09/2011 Bielefeld University, Germany
Bachelor of Science Biochemistry
Selected Scholarships
Boehringer Ingelheim Fonds
Bayer Science & Education Foundation
German National Merit Foundation
Publications
Optical Structural Analysis of Individual α-Synuclein Oligomers
– Angewandte Chemie International Edition
(2018)
57,
4886
(doi: 10.1002/anie.201710779)
Monomeric and fibrillar α-synuclein exert opposite effects on the catalytic cycle that promotes the proliferation of Aβ42 aggregates.
– Proceedings of the National Academy of Sciences of the United States of America
(2017)
114,
8005
(doi: 10.1073/pnas.1700239114)
Ultrasensitive Measurement of Ca2+ Influx into Lipid Vesicles Induced by Protein Aggregates.
– Angew Chem Int Ed Engl
(2017)
56,
7750
(doi: 10.1002/anie.201700966)
Ultrasensitive Measurement of Ca2+ Influx into Lipid Vesicles Induced by Protein Aggregates
– Angewandte Chemie
(2017)
129,
7858
(doi: 10.1002/ange.201700966)
A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity.
– Proceedings of the National Academy of Sciences
(2017)
114,
e1009
(doi: 10.1073/pnas.1610586114)
β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces
– Sci Rep
(2016)
6,
36010
(doi: 10.1038/srep36010)
Mutations associated with familial Parkinson's disease alter the initiation and amplification steps of α-synuclein aggregation.
– Proc Natl Acad Sci U S A
(2016)
113,
10328
(doi: 10.1073/pnas.1604645113)
Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein
– Proc Natl Acad Sci U S A
(2016)
113,
7065
(doi: 10.1073/pnas.1601899113)
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