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Centre for Misfolding Diseases

Michele Sanguanini

Publications

Effects of system complexity on protein aggregation in neurodegeneration
M Sanguanini
(2021)
(doi: 10.17863/CAM.71909)
Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation
E Kelmer Sacramento, JM Kirkpatrick, M Mazzetto, M Baumgart, A Bartolome, S Di Sanzo, C Caterino, M Sanguanini, N Papaevgeniou, M Lefaki, D Childs, S Bagnoli, E Terzibasi Tozzini, D Di Fraia, N Romanov, PH Sudmant, W Huber, N Chondrogianni, M Vendruscolo, A Cellerino, A Ori
– Molecular systems biology
(2020)
16,
e9596
(doi: 10.15252/msb.20209596)
Complexity in Lipid Membrane Composition Induces Resilience to Aβ42 Aggregation
M Sanguanini, KN Baumann, S Preet, S Chia, J Habchi, TPJ Knowles, M Vendruscolo
– ACS Chem Neurosci
(2020)
11,
1347
(doi: 10.1021/acschemneuro.0c00101)
A continuous model of physiological prion aggregation suggests a role for Orb2 in gating long-term synaptic information.
M Sanguanini, A Cattaneo
– Royal Society open science
(2018)
5,
180336
(doi: 10.1098/rsos.180336)
Transcriptome Analysis Introduction and Examples from the Neurosciences
A Cellerino, M Sanguanini
(2018)
(doi: 10.1007/978-88-7642-642-1)
Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes.
J Habchi, S Chia, C Galvagnion, TCT Michaels, MMJ Bellaiche, FS Ruggeri, M Sanguanini, I Idini, JR Kumita, E Sparr, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
– Nat Chem
(2018)
10,
673
(doi: 10.1038/s41557-018-0031-x)

Graduate student

Telephone number

01223 748844

College

Gonville & Caius College

    Study at Cambridge

    About the University

    Research at Cambridge