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Centre for Misfolding Diseases

Research Associate

Publications

Small molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer’s disease
G Heller, F Aprile, T Michaels, R Limbocker, M Perni, FS Ruggeri, B Mannini, T Löhr, M Bonomi, C Camilloni, A De Simone, I Felli, R Pierattelli, T Knowles, C Dobson, M Vendruscolo
(2019)
729392
Determination of protein structural ensembles using cryo-electron microscopy.
M Bonomi, M Vendruscolo
– Curr Opin Struct Biol
(2019)
56,
37
Effects of α-tubulin acetylation on microtubule structure and stability
L Eshun-Wilson, R Zhang, D Portran, M Nachury, D Toso, T Lohr, M Vendruscolo, M Bonomi, J Fraser, E Nogales
(2019)
516591
Determination of Structural Ensembles of Proteins: Restraining vs Reweighting.
R Rangan, M Bonomi, GT Heller, A Cesari, G Bussi, M Vendruscolo
– Journal of chemical theory and computation
(2018)
14,
6632
Bayesian Weighing of Electron Cryo-Microscopy Data for Integrative Structural Modeling
M Bonomi, S Hanot, CH Greenberg, A Sali, M Nilges, M Vendruscolo, R Pellarin
– Structure (London, England : 1993)
(2018)
27,
175
Biasing Smarter, Not Harder, by Partitioning Collective Variables into Families in Parallel Bias Metadynamics
A Prakash, CD Fu, M Bonomi, J Pfaendtner
– J Chem Theory Comput
(2018)
14,
4985
Structural Ensemble Modulation upon Small-Molecule Binding to Disordered Proteins
GT Heller, M Bonomi, M Vendruscolo
– J Mol Biol
(2018)
430,
2288
Reversible inhibition of the ClpP protease via an N-terminal conformational switch
S Vahidi, ZA Ripstein, M Bonomi, T Yuwen, MF Mabanglo, JB Juravsky, K Rizzolo, A Velyvis, WA Houry, M Vendruscolo, JL Rubinstein, LE Kay
– Proc Natl Acad Sci U S A
(2018)
115,
e6447
Simultaneous Determination of Protein Structure and Dynamics Using Cryo-Electron Microscopy.
M Bonomi, R Pellarin, M Vendruscolo
– Biophysical Journal
(2018)
114,
1604
A Bayesian Integrative Structure Model of the Yeast Centrosome
S Viswanath, M Bonomi, SJ Kim, VA Klenchin, K Taylor, KC Yabut, NT Umbreit, J Meehl, MH Jones, J Velazquez-Muriel, M Winey, I Rayment, TN Davis, A Sali, ED Muller
– Biophysical Journal
(2018)
114,
35A
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Postdoctoral researcher

Telephone number

01223 336366 (shared)