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Centre for Misfolding Diseases

Dr Minkoo Ahn

Research Associate

Publications

Trodusquemine enhances Aβ 42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes
R Limbocker, S Chia, FS Ruggeri, M Perni, R Cascella, GT Heller, G Meisl, B Mannini, J Habchi, TCT Michaels, PK Challa, M Ahn, ST Casford, N Fernando, CK Xu, ND Kloss, SIA Cohen, JR Kumita, C Cecchi, M Zasloff, S Linse, TPJ Knowles, F Chiti, M Vendruscolo, CM Dobson
– Nature Communications
(2019)
10,
225
(doi: 10.1038/s41467-018-07699-5)
Chemical and mechanistic analysis of photodynamic inhibition of Alzheimer's β-amyloid aggregation.
M Ahn, BI Lee, S Chia, J Habchi, JR Kumita, M Vendruscolo, CM Dobson, CB Park
– Chem Commun (Camb)
(2019)
55,
1152
(doi: 10.1039/c8cc09288e)
Systematic Development of Small Molecules to Inhibit Specific Microscopic Steps of Amyloid-Beta42 Aggregation in Alzheimer's Disease
S Chia, J Habchi, R Limbocker, B Mannini, M Ahn, M Perni, O Hansson, P Arosio, JR Kumita, PK Challa, SIA Cohen, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
– Biophysical Journal
(2018)
114,
225a
(doi: 10.1016/j.bpj.2017.11.1253)
Application of Lysine-specific Labeling to Detect Transient Interactions Present During Human Lysozyme Amyloid Fibril Formation.
M Ahn, CA Waudby, A Bernardo-Gancedo, E De Genst, A Dhulesia, X Salvatella, J Christodoulou, CM Dobson, JR Kumita
– Scientific Reports
(2017)
7,
15018
(doi: 10.1038/s41598-017-14739-5)
Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer's disease
J Habchi, S Chia, R Limbocker, B Mannini, M Ahn, M Perni, O Hansson, P Arosio, JR Kumita, PK Challa, SIA Cohen, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
– Proceedings of the National Academy of Sciences
(2016)
114,
e200
(doi: 10.1073/pnas.1615613114)
The Significance of the Location of Mutations for the Native-State Dynamics of Human Lysozyme.
M Ahn, CL Hagan, A Bernardo-Gancedo, E De Genst, FN Newby, J Christodoulou, A Dhulesia, M Dumoulin, CV Robinson, CM Dobson, JR Kumita
– Biophysical Journal
(2016)
111,
2358
(doi: 10.1016/j.bpj.2016.10.028)
Analysis of the Native Structure, Stability and Aggregation of Biotinylated Human Lysozyme
M Ahn, E De Genst, GS Kaminski Schierle, M Erdelyi, CF Kaminski, CM Dobson, JR Kumita
– PLoS One
(2012)
7,
e50192
(doi: 10.1371/journal.pone.0050192)
Investigating the effects of a chemical probe on the native structure and misfolding of human lysozyme
M Ahn, E De Genst, GK Schierle, M Erdelyi, C Kaminski, C Dobson, J Kumita
– PROTEIN SCIENCE
(2012)
21,
104
(link to publication)
Removal of intact β2-microglobulin at neutral ph by using seed-conjugated polymer beads prepared with β2-microglobulin-derived peptide (58-67).
S Kang, JE Yang, J Kim, M Ahn, HJ Koo, M Kim, Y-S Lee, SR Paik
– Biotechnology progress
(2011)
27,
521
(doi: 10.1002/btpr.562)
Nanoporous protein matrix made of amyloid fibrils of β2-microglobulin.
M Ahn, S Kang, HJ Koo, J-H Lee, Y-S Lee, SR Paik
– Biotechnology Progress
(2010)
26,
1759
(doi: 10.1002/btpr.466)
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Postdoctoral researcher

Telephone number

01223 763845 (shared)

College

St John's College

    Study at Cambridge

    About the University

    Research at Cambridge