Senior Research Fellow
Publications
Microfluidic Diffusion Viscometer for Rapid Analysis of Complex Solutions.
– Analytical Chemistry
(2016)
88,
3488
(doi: 10.1021/acs.analchem.5b02930)
Microfluidic diffusion analysis of the sizes and interactions of proteins under native solution conditions
– ACS nano
(2015)
10,
333
(doi: 10.1021/acsnano.5b04713)
A Rational Design Strategy for the Selective Activity Enhancement of a Molecular Chaperone toward a Target Substrate.
– Biochemistry
(2015)
54,
5103
(doi: 10.1021/acs.biochem.5b00459)
Cell surface localised Hsp70 is a cancer specific regulator of clathrin-independent endocytosis
– FEBS Letters
(2015)
589,
2747
Rational design of antibodies targeting specific epitopes within intrinsically disordered proteins
– Proceedings of the National Academy of Sciences
(2015)
112,
9902
(doi: 10.1073/pnas.1422401112)
Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation
– Proceedings of the National Academy of Sciences of the United States of America
(2015)
112,
E1994
(doi: 10.1073/pnas.1421204112)
Structure and dynamics of the integrin LFA-1 I-domain in the inactive state underlie its inside-out/outside-in signaling and allosteric mechanisms.
– Structure
(2015)
23,
745
(doi: 10.1016/j.str.2014.12.020)
The CamSol method of rational design of protein mutants with enhanced solubility
– Journal of Molecular Biology
(2015)
427,
478
(doi: 10.1016/j.jmb.2014.09.026)
Structure of a low-population intermediate state in the release of an enzyme product.
– Elife
(2015)
4,
e02777
(doi: 10.7554/elife.02777)
Structural characterization of toxic oligomers that are kinetically trapped during alpha-synuclein fibril formation
– PROTEIN SCIENCE
(2015)
24,
136
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