Publications
Proteome-wide observation of the phenomenon of life on the edge of solubility
– Proceedings of the National Academy of Sciences of the United States of America
(2019)
117,
1015
(doi: 10.1073/pnas.1910444117)
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes.
– Nature communications
(2019)
10,
225
(doi: 10.1038/s41467-018-07699-5)
Small molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer’s disease
(2019)
729392
(doi: 10.1101/729392)
Differential interactome and innate immune response activation of two structurally distinct misfolded protein oligomers.
– ACS chemical neuroscience
(2019)
10,
3464
(doi: 10.1021/acschemneuro.9b00088)
Stabilization and Characterization of Cytotoxic Aβ40 Oligomers Isolated from an Aggregation Reaction in the Presence of Zinc Ions
– ACS Chemical Neuroscience
(2018)
9,
2959
(doi: 10.1021/acschemneuro.8b00141)
Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine.
– ACS chemical biology
(2018)
13,
2308
(doi: 10.1021/acschembio.8b00466)
Toxic HypF-N Oligomers Selectively Bind the Plasma Membrane to Impair Cell Adhesion Capability
– Biophysical Journal
(2018)
114,
1357
(doi: 10.1016/j.bpj.2018.02.003)
Systematic Development of Small Molecules to Inhibit Specific Microscopic Steps of Amyloid-Beta42 Aggregation in Alzheimer's Disease
– Biophysical Journal
(2018)
114,
225a
(doi: 10.1016/j.bpj.2017.11.1253)
Modulating Amyloid-Beta Aggregation to Reduce the Toxicity of its Oligomeric Aggregates
– Biophysical Journal
(2018)
114,
430a
(doi: 10.1016/j.bpj.2017.11.2382)
Delivery of Native Proteins into C. Elegans Using a Transduction Protocol Based on Lipid Vesicles
– Scientific Reports
(2017)
7,
15045
(doi: 10.1038/s41598-017-13755-9)
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